EE62 Direct and Indirect Costs of Multiple Sclerosis in China

Multiple sclerosis (MS) is a chronic disabling neurological disease affecting both physical and mental functions, resulting in impaired quality of life for patients their caregivers. Although studies Western countries have demonstrated that MS imposes considerable direct indirect costs on healthcare systems societies, empirical research China limited regarding the economic burden MS. This study aimed to describe due China, stratified by Expanded Disability Status Scale (EDSS) score. The analysis was conducted using data from Adelphi Disease Specific Program, point-in-time survey neurologists rehabilitation specialists between June September 2021. Demographic information, employment status, resource utilization during previous 12 months were collected. Costs calculated combining unit expenditure extracted official databases. Generalized linear models (GLMs) with log link gamma distribution used model association current EDSS score (presented as percentage increase per baseline cost), adjusting age, sex, insurance type. 679 scores included (female 66.9%; mean age 43.2 years, SD 13.1). GLM showed increased significantly associated increasing medical (+16.9%, p<0.001, RMB 32387.95), including cost hospitalization (+23.0%, p=0.057), tests (+5.94%, p<0.001), symptomatic treatment (+12.9%, p=0.005), concomitant conditions (+30.4%, p<0.001). Increasing also rising non-medical (+46.5%, 1622.342) (+34.3%, 23156.23). rise costs. suggests interventions can reduce disability progression could help save downstream lessen societal burden.